I'm surprised Foxwoods and Mohegan are still open. Every other casino in the area are closed! Does anyone think they they will still be open next weekend?
A friend posted this a few minutes ago...”Hi everyone. A late nite update. There are 2951 confirmed cases of COVID-19 in the US as of this post. That is up almost exactly 700 since yesterday’s number. Multiply that by five and that may be a conservative guess on true number of active cases. I’m not gonna go into death rates now, except to say Italy is being overwhelmed with a 9-10% mortality rate. I’ve seen the videos and read the posts. It’s a disaster there. Italy remains on lockdown and will be on that for a good while. Spain is on lockdown. That is everyone is on home quarantined except the obvious exceptions. All businesses are closed except groceries, pharmacies, and essential supply stores. France and Israel are on lockdown as of tonight. All stores, restaurants, bars, shops, etc are closed and basically on lockdown. ? Germany is next followed by the UK. The US Military is on travel restriction and soldiers are staying at bases or being positioned for where they are needed. Do not be surprised to see air travel shut down in the United States in the next couple of days. That is what I am hearing. Go ahead and begin Self Quarantine for your families at home.?? Get your final supplies. Prepare for mandatory quarantine except for medical workers, police, fire, and essential personnel. We must stay under the health care curve! Please forward this to your friends. I am sorry that I do not have better news. All of the people I have spoken to today, which has been a ton, agree and recommend this. I am counting on you Sabine Solika and each and everyone of y’all. Be calm, follow the program, and be well...???? Doc ??
You guys are all AP, all math and science oriented..
The one situation where an entire, closed population was tested was the Diamond Princess cruise ship and its quarantine passengers. The case fatality rate there was 1.0%, but this was a largely elderly population, in which the death rate from Covid-19 is much higher.
Projecting the Diamond Princess mortality rate onto the age structure of the U.S. population, the death rate among people infected with Covid-19 would be 0.125%. But since this estimate is based on extremely thin data — there were just seven deaths among the 700 infected passengers and crew — the real death rate could stretch from five times lower (0.025%) to five times higher (0.625%). It is also possible that some of the passengers who were infected might die later, and that tourists may have different frequencies of chronic diseases — a risk factor for worse outcomes with SARS-CoV-2 infection — than the general population. Adding these extra sources of uncertainty, reasonable estimates for the case fatality ratio in the general U.S. population vary from 0.05% to 1%.
That huge range markedly affects how severe the pandemic is and what should be done. A population-wide case fatality rate of 0.05% is lower than seasonal influenza. If that is the true rate, locking down the world with potentially tremendous social and financial consequences may be totally irrational. It’s like an elephant being attacked by a house cat. Frustrated and trying to avoid the cat, the elephant accidentally jumps off a cliff and dies.
Could the Covid-19 case fatality rate be that low? No, some say, pointing to the high rate in elderly people. However, even some so-called mild or common-cold-type coronaviruses that have been known for decades can have case fatality rates as high as 8% when they infect elderly people in nursing homes. In fact, such “mild” coronaviruses infect tens of millions of people every year, and account for 3% to 11%of those hospitalized in the U.S. with lower respiratory infections each winter.
"Black Tea which contains Theaflavin could be potential SARSâ€CoVâ€2 RdRp inhibitor.Dr Pritom Choudhury, @TRATocklai Scientist work have been cited that Theaflavin & Polyphenols inhibit entry of Hepatitis C virus. #COVID19 @WHO @PMOIndia @CimGOI @DoC_GoI "
There is a popular tweet that black tea containing Theaflavin that is the natural inhibitor of Covid 19. In UK, black tea sold out in supermarket before toilet paper.
Black tea cannot cure Covid 19. But it will reduce your chance of getting Covid 19 if you drank enough. Many now believe that.
The original paper is published on Journal of Medical Virology. The publisher is Wiley, very credible.Originally Posted by 21forme
It has a fancy title, "The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase". But basically the author is saying that black tea is rich of Theaflavin which is the inhibitor of many viruses including Covid 19.
Hope people are open-minded.
Link to the study : https://onlinelibrary.wiley.com/doi/...1002/jmv.25761
It should be noted, however, that this is based on numerical computation and simulation on a library of +80 popular Chinese Medicines. They found that Theaflavin had a lower binding energy to the catalytic active site of Rd-RNAP for SARS-CoV-2 in silico compared to other molecules. The research team has not come to the conclusion on the mechanisms or success of in vivo inhibition. Rather, this compound is to be added in-queue as a lead compound for pharmacological study. (Note the bolded part.)
Just because it has a fancy title, does not mean that what is presented it correct or true. The nature of the article is not to make a grand claim (like you did) but rather offer to other researchers possible novel compounds to find and research for successful inhibition of RNA polymerization.
While the author did mention black tea as a source of theaflavin, and that inhibition is successful with a given strain of SARS-CoV-2, does not mean that ingestion of theaflavin-containing black tea will either protect you (PrEP) nor treat COVID19 (PEP). Rather, the compound itself will most likely be used as a stand-alone pharmaceutical in the treatment of COVID19 if and when scientific consensus is reached on its inhibitory effects across different strains of the virus and both in vitro and in vivo.
To be "open-minded" here is to :
-Read the paper
-Understand the nuance of what the author is saying
-Respect that this is strictly for discovery and not making a declarative statement on a cure
One should know. The study is originally targeting Covid 2 or SARS, the Corona virus causing outbreak in 2002. And the authors claim Theaflavin is effective on all Corona virus family. I don't know if the theory is valid. Just saw it got tweeted enough to cause the public to buy out all black tea like toilet paper in some places. So it is fun to report it and that is enough for some people use it to attack me.
Last edited by BJGenius007; 03-24-2020 at 03:27 PM.
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