The darkest casino I was ever in is the Santa Fe Station in LV 10-12 years ago. One area was so dark I actually had trouble seeing my cards. It was also the grubbiest casino I have ever seen. Pictures from a Google search today appear much brighter and cleaner than I remember.
Last year, I sat next to a table with a drunk couple swearing loudly in three languages. I joined their conversation (mostly in English) and had a ball.
My answer to the OP's question: No, a casino's ambiance doesn't matter to me.
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